Resources. Seeing the unseen: Vanderbilt science hub helps set a standard for innovative microbiome research, education. Stevenson Professor , Chemistry: john.a.mclean@Vanderbilt.Edu ; Social Media View @VuBiome’s profile on Twitter; To Contact VMI or Join the Vanderbilt Listserv. Stevenson Professor of Chemistry Department of Chemistry Vanderbilt University 7330 Stevenson Center Nashville, TN 37235 Phone: 615-322-1195 Email: john.a.mclean@vanderbilt…

Vanderbilt © and the Vanderbilt logos are registered trademarks of The Vanderbilt University. glycosylation, phosphorylation, ubiquination, sumoylation, etc.) Vanderbilt®, Vanderbilt University®, V Oak Leaf Design®, Star V Design® and Anchor Down® are trademarks of The Vanderbilt University, Nuclear Magnetic Resonance Spectroscopy (NMR), New technique maps twin faces of smallest Janus nanoparticles, Dr. Michal Kliman (McLean group) featured on the cover of October 10th issue of C&ENews for mass spectrometry and lipidomics", John McLean was awarded Excellence in Teaching, That Alcohol Is Going On Your Permanent Record, Vanderbilt-led team to develop 'microbrain' to improve drug testing, David Cliffel, John McLean, and colleagues have big hopes on a tiny device, New tool for mining bacterial genome for novel drugs, Vanderbilt awarded $16.5 million agreement to determine how toxic agents affect human cells, 'Thought Leader' named for ion mobility mass spectrometry research, Site Development: Digital Strategies (Division of Communications). VICB Physical Chemistry Mass spectrometry Lipidomics Chemical Biology Biophysical Chemistry Bioanalytical Chemistry Analytical Chemistry IM-MS provides separations on the basis of apparent surface area (ion-neutral collision cross section) and mass-to-charge (m/z), respectively.
Vanderbilt University is committed to principles of equal opportunity and affirmative action. Allwardt V, Ainscough AJ, Viswanathan P, Sherrod SD, McLean JA, Haddrick M, Pensabene V, Translational Roadmap for the Organs-on-a-Chip Industry toward Broad Adoption, Bioengineering, 2020, 7, 112. Published 2020 155.

In collaboration with Prof. Janet Macdonald, the McLean Group (Andrzej Balinski and Prof. John McLean) are leveraging their chemical expertise to produce hand sanitizer for Vanderbilt and the greater Nashville area. Development of selective IM-MS shift reagents for high confidence level identification in proteomics, glycomics, lipidomics, and metabolomics.

Biomolecular structural information is interpreted by comparing experimentally obtained collision cross-sections in the context of those obtained via molecular dynamics simulations. His group applies these strategies to forefront translational research areas in drug discovery, personalized medicine, and ‘human-on-chip’ synthetic biology platforms. Vanderbilt University is committed to principles of equal opportunity and affirmative action. Mar. Vanderbilt®, Vanderbilt University Medical Center®, V Oak Leaf Design®, Monroe Carell Jr. Children’s Hospital at Vanderbilt® and Vanderbilt Health® are trademarks of The Vanderbilt University.

Recent News. McLean and colleagues focus on the conceptualization, design, and construction of structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology.

John McLean is the Stevenson Associate Professor of Chemistry at Vanderbilt University, co-Director of the Vanderbilt Automated Biosystems Core, and Deputy Director of the Vanderbilt Institute for Integrative Biosystems Research and Education.

John McLean is the Stevenson Associate Professor of Chemistry at Vanderbilt University, co-Director of the Vanderbilt Automated Biosystems Core, and Deputy Director of the Vanderbilt Institute for Integrative Biosystems Research and Education. Accessibility information. Explore scientific resources, protocols and other pages. John A. McLean is Stevenson Professor of Chemistry, Director of the Center for Innovative Technology, and Deputy Director of the Institute for Integrative Biosystems Research and Education at Vanderbilt … Site Development: Digital Strategies (Division of Communications) McLean Research Group Retools for Hand Sanitizer Production.

Development of imaging IM-MS instrumentation for multidimensional imaging/characterization of biomarker species from thin tissue sections and microarrays. John A. McLean is Stevenson Professor of Chemistry, Director of the Center for Innovative Technology, and Deputy Director of the Institute for Integrative Biosystems Research and Education at Vanderbilt University.

Following postdoctoral training at at Forschungszentrum Jülich in Germany and at Texas A&M University with Prof. David H. Russell in biological mass spectrometry he joined the Vanderbilt faculty in 2006. Microbiome links diet to health. More . Accessibility information. John A. McLean is Stevenson Professor of Chemistry, Director of the Center for Innovative Technology, and Deputy Director of the Institute for Integrative Biosystems Research and Education at Vanderbilt University. Copyright © 2020 Vanderbilt University Medical Center.

Host-microbe interactions in the gut. He has published over 175 manuscripts, book chapters, and patents and serves as an Associate Editor for Nature Molecular Phenomics and on the Editorial Boards of several leading scientific journals. HPV-Associated Cancer ConsorTIum at VandErbilt Featured community Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using …

Combining microfluidic separation strategies with IM-MS for fundamental biomolecular characterization in systems biology. All rights reserved. All rights reserved. Access citations of our published works for your reference manager. Vanderbilt University is committed to principles of equal opportunity and affirmative action.

Prof. McLean completed his PhD at George Washington University in 2001 under the direction of Prof. Akbar Montaser, performed postdoctoral research at Forschungszentrum Jülich in Germany, and then was a postdoctoral at Texas A&M University with Prof. David H. Russell in biological mass spectrometry.

John McLean Archives The most popular research stories of 2015.

Education, Training, and Career Development, Director, Center for Innovative Technology, Ph.D., George Washington University, Washington, District of Columbia (2001), M.Phil., George Washington University, Washington, District of Columbia (1998), B.S., University of Michigan, Ann Arbor, Michigan (1995).

Dec. 28, 2015—With discoveries ranging from the origins of consciousness to the end of the universe, 2015 was a year of incredibly diverse research at Vanderbilt University. Centers of Innovation member, John McLean of Vanderbilt University, shares his point of view on the meaning of innovation and what drives innovation forward. Vanderbilt University Medical Center is committed to principles of equal opportunity and affirmative action. All rights reserved.

Accessibility information. Biomolecular structural information is interpreted by comparing experimentally obtained collision cross-sections in the context of those obtained via molecular dynamics simulations.
04.14.2020.

Prof. McLean and his group leverage these strengths with those across Vanderbilt, nationally, and Internationally in academe, industry, and government through cutting-edge interdisciplinary collaborations. John McLean John A. McLean is Stevenson Professor of Chemistry, Director of the Center for Innovative Technology, and Deputy Director of the Institute for Integrative Biosystems Research and Education at Vanderbilt University. Sophisticated ion mobility-mass spectrometry platforms were subsequently released by multiple leading global scientific instrument manufacturers At Vanderbilt, McLean and colleagues focus on the conceptualization, design, and construction of structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology as well as nanotechnology. IM-MS provides separations on the basis of apparent surface area (ion-neutral collision cross section) and mass-to-charge (m/z), respectively. 20, 2014— Vanderbilt's John McLean has received Agilent Technology's Thought Leader Award in recognition of his contributions to ion mobility mass spectrometry.

To identify and structurally characterize biomolecules from complex samples, we perform rapid (µs-ms) two-dimensional gas-phase separations using ion mobility-mass spectrometry (IM-MS) techniques.

The most popular research stories of 2015, Symposium on impact of ‘omics on medicine set for March 23, Eleven faculty honored with endowed chairs, Vanderbilt awarded $16.5 million agreement to determine how toxic agents affect human cells, Vanderbilt-led team to develop ‘microbrain’ to improve drug testing. Seeing the unseen: Vanderbilt science hub helps set a standard for innovative microbiome research, education.

Publications.

VUCast: Fight club to save lives; Seeing in tune; Best Vanderbilt fans! Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches. Our research focuses on the design, construction, and application of advanced technologies for structural mass spectrometry, in particular, for studies in structural proteomics, systems biology, and biophysics. Construction of advanced laser optical strategies for high-throughput screening of drug-ligand interactions. To identify and structurally characterize biomolecules from complex samples, we perform rapid (µs-ms) two-dimensional gas-phase separations using ion mobility-mass spectrometry (IM-MS) techniques.

on protein secondary and tertiary structure?

Picache JA, May JC, McLean JA, Chemical Class Prediction of Unknown Biomolecules Using …

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154. Chemistry from the University of Michigan and his PhD from the George Washington University.

Creating bacterial ‘fight clubs’ to discover new drugs, Symposium on impact of ‘omics on medicine set for March 23, ‘Thought Leader’ named for ion mobility mass spectrometry research, Eleven faculty honored with endowed chairs, Significant progress toward creating “benchtop human” reported, Vanderbilt awarded $16.5 million agreement to determine how toxic agents affect human cells, New tool for mining bacterial genome for novel drugs, Site Development: Digital Strategies (Division of Communications). John McLean is the Stevenson Associate Professor of Chemistry at Vanderbilt University, co-Director of the Vanderbilt Automated Biosystems Core, and Deputy Director of the Vanderbilt Institute for Integrative Biosystems Research and Education.

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